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The puzzling relationship between human leukocyte antigen HLA genes and celiac disease
Carlo Catassi, Giulia Naspi Catassi
The human leukocyte antigen (HLA) system, i.e., the major histocompatibility complex (MHC) in humans, plays a pivotal role in the antigen presentation of intracellular and extracellular peptides and...
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Systematic Review/Meta Analysis
Is water exchange superior to water immersion for colonoscopy? A systematic review and meta-analysis
Zhihao Chen, Zhengqi Li, Xinying Yu, Guiqi Wang
Background/Aims: Recently, water exchange (WE) instead of water immersion (WI) for colonoscopy has been proposed to decrease pain and improve adenoma detection rate (ADR). This systematic rev...
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Original Article
Genetic susceptibility for celiac disease is highly prevalent in the Saudi population
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Abdulrahman Al-Hussaini, Hanan Alharthi, Awad Osman, Nezar Eltayeb-Elsheikh, Aziz Chentoufi
Background/Aim: To determine the frequency of celiac disease (CD)-predisposing human leukocyte antigen (HLA)-DQ genotypes in the Saudi population, where the prevalence of CD is 1.5%...
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